No, you can't run diatoms 24x7. The filter media get clogged very quickly,
typically within a few hours. Diatom filters are used as occasional water
polishing filters, not as permanent filters.
Maybe you can't, but I can.
If your tank is so dirty it clogs a diatom filter in under a week or two
you have bigger problems than trying to make it crystal clear. Try some elbow
grease and big water changes.
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