Online software for optimizing expression of recombinant proteins
Primo Optimum is designed for optimal expression of genes of interest
in a host organism (e.g., E. Coli, yeast, plants, or mammalian cell lines). Different species have different codon usage frequencies. For high level protein expression in a host, optimization of the gene sequence to match the host's codon bias increases yield and is frequently necessary. Primo Optimum provides a tool for optimizing gene expression in any host species and designs primers for the one-step PCR synthesis of the optimal gene. In addition it checks for a number of factors that might be detrimental for protein expression. Please visit online at http://www.changbioscience.com/primo/ Comments and suggestions will be greatly appreciated. Thanks. Chang |
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