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-   -   Online software for optimizing expression of recombinant proteins (https://www.gardenbanter.co.uk/plant-biology/13773-online-software-optimizing-expression-recombinant-proteins.html)

Chang Zhu 05-04-2003 03:20 PM

Online software for optimizing expression of recombinant proteins
 
Primo Optimum is designed for optimal expression of genes of interest
in a host organism (e.g., E. Coli, yeast, plants, or mammalian cell
lines). Different species have different codon usage frequencies. For
high level protein expression in a host, optimization of the gene
sequence to match the host's codon bias increases yield and is
frequently necessary. Primo Optimum provides a tool for optimizing
gene expression in any host species and designs primers for the
one-step PCR synthesis of the optimal gene. In addition it checks for
a number of factors that might be detrimental for protein expression.
Please visit online at

http://www.changbioscience.com/primo/

Comments and suggestions will be greatly appreciated.

Thanks.

Chang


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