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Plant Metabolic Network News Announcement
Dear Plant Researchers,
The Plant Metabolic Network (PMN) is pleased to announce the initial launch of its official web site (http://plantcyc.org) and the first release of PlantCyc, a comprehensive biochemical pathway reference database dedicated to the plant kingdom. The PMN is an NSF-funded collaborative project among databases and biochemists with a common goal to build a broad network of plant metabolic pathway databases. The central database of PMN, PlantCyc (version 1.0), has over 500 pathways and about 3000 enzymes involved in primary and secondary metabolism, consolidated from over 290 plant species. The majority of these pathways come from AraCyc (version 4.5, http://www.arabidopsis.org/biocyc/index.jsp) and MetaCyc (version 12.0, http://metacyc.org). Many pathway diagrams were manually extracted from the plant literature. They are either supported by experimental evidence or are based on expert hypotheses. A small portion of the pathways were computationally predicted but validated by curators with supporting evidence in the literature. Evidence codes are attached to pathways and to enzymes to indicate data quality. In addition to PlantCyc, the PMN will develop and host a collection of single-species databases like that of AraCyc (Arabidopsis). We are currently developing databases for several agronomically important plants including poplar, soybean, wheat and maize. PMN will also host databases developed elsewhere such as RiceCyc (rice), MedicCyc (medicago) and LycoCyc (tomato). These single-species pathway databases place the sequenced and annotated genomes or ESTs in a biochemical context to facilitate the discovery of enzymes and the engineering of metabolic pathways. They also provide a platform for users to display and analyze functional genomics data, such as those generated from microarray and metabolomic experiments. Nearly 30 plant biochemists serve on the PMN editorial board to provide overall vision and guidance to the PMN project and they play an active role in ensuring the high quality of the information present in the PMN. The enhancement of the PMN databases is an ongoing effort. All users are encouraged to send corrections, feedback, and new data. Please contact us at . The PMN Team |
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