I'm assuming these are fire ants, right?

we've long used uncooked regular grits on fire ant mounds. It has to be the
regular cooking grits, not the quick ones. sprinkle around the perimeter of
the mound. be generous. You may have to chase them around the property a
couple times as some of the survivors start a new colony. It's always worked
for us. It's funny to see the ants get so excited at all the free food.