In article .com.au,
Daniel Hanna wrote:

In Tim Tompkins wrote:
"Triforine is a "restricted use" pesticide (RUP) with an EPA toxicity
classification of I (highly toxic). Check with specific state
regulations for local restrictions which may apply. Products
containing triforine must bear the Signal Word "Danger" on their label.
"

So much for labels. Read the text, Tim! Has it killed anyone? Caused
cancer, perhaps? Maybe some birth defects or mutations? No? Perhaps
some soil persistence issues, then? Or maybe it accumulates in the
human body over time, then? No?

Triforine doesn't even kill aphids, Tim.

Now read http://www.roseshawaii.org/msds/orthenex.htm and see what it
says. Bingo, the dangerous part of this combination product is acephate.
It can poison a foetus and cause organ toxicity like other anti-
cholinesterase (organophosphate) chemicals. Even then it's pretty minor
league, compared to others in common garden use. Try looking up
dimethoate or diazinon for a real scare.

You're putting too fine point on it, Daniel. MSDS in the US requires
labeling for " inert ingredients [that] may be hazardous chemicals,
as defined by the Federal OSHA Hazard Communication Standard (29 CFR
1910.1200). " So even if you are right that Triforine itself is not
hazardous, the *formulation* has the DANGER label because it can cause
permanent damage to the eyes and blindness. We have no access to
triforine without the accompanying dangerous inert ingredient.

The label for Triforine EC states:

POTENTIAL HEALTH EFFECTS
Acute Toxicity (Primary Routes of Exposure)
*****Eye: This substance is a severe eye irritant and could cause
permanent damage to your eyes and blindness. The degree of the injury
will depend on the amount of material that gets into the eye and the
speed and thoroughness of the first aid treatment. Signs and symptoms
may include pain, tears, swelling, redness, and blurred vision.*****

In the UK:
http://www.pan-uk.org/pestnews/pn33/pn33p3.htm

They don't know what has caused the *permanent corneal damage*, whether
any one of the components or the combination. The point is:

**Animal tests show severe eye and skin irritancy**
Toxicity data on the Roseclear concentrate was submitted to the
Pesticides Safety Directorate (PSD) of MAFF in April 1995 and included
studies on skin and eye irritancy. The studies, using the concentrated
product (the form in which it is sold), on eye irritancy caused most
concern. The corneas of test animals were severely damaged, resulting
in the permanent clouding of vision, indicating that Roseclear is an
extremely severe eye irritant, and should be classified as 'Risk of
Serious Damage to Eyes'. In the skin irritation study, the concentrated
product was applied directly to skin for four hours. The* severe
effects which followed indicate that the product is an extreme skin
irritant.

It more useful to know the followng from
http://www.rosemania.com/Chemical_Spray_Safety.htm:

"The most toxic pesticides carry the word DANGER on the label, are
listed as highly toxic and are classified by the Environmental
Protection Agency as Category I pesticides. Based on lethality
information, it would only take ingestion of a few drops of a liquid or
about 3.5 grams (remember that there are 454 grams per pound) of a
solid to kill a 150 lb man. Category I pesticides with this lethality
potential can only be applied by licensed applicators, and are not
available for general use by the home gardener. However, some
pesticides available to the home gardener are listed as Category I
pesticides based on their ability to produce severe skin and/or eye
damage. These pesticides include: *Orthenex,* Vendex, Isotox, Mavrik
2E, Captan dust or powder, *Triforine EC, * *Lime Sulfur and Copper
Sulfate (99%+)*. (emphasis added)"