Thread: Roundup Unready
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Old 07-09-2003, 08:12 PM
Henry Kuska
 
Posts: n/a
Default Roundup Unready

billo said: " The paradigm for glyphosate is the Non-Hodgkins lymphoma
example, which
is also association with the development of Non-Hodgkins lymphoma in
which univariate analysis showed a weak association between glyphosate
and NHL. (Hardell L, Eriksson M. A Case-control study of non-Hodgkin
lymphoma and exposure to pesticides. Cancer 1999; 85: 1353-60.) Paghat
and her ilk touted this as the definitive study, in spite of the fact
that the authors also cautioned against such hyperbole. And, of
course, when the final study came out two years later, the association
between Roundup and NHL disappeared under multivariate analysis. It
turned out that overexposure to a cocktail *multiple* pesticides and
herbicides acting together, not Roundup, increased the risk. (Hardell,
L, Eriksson, M., Nordstrom M. Exposure to pesticides as risk factor
for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of
two Swedish case-control studies. Leuk Lymphoma. 2002
May;43(5):1043-9.) Of course, at that point Eriksson, et al. all
suddenly became shills for Monsanto instead of the paradigms of truth
that they were just months before. My how the mighty have fallen.


VERY RECENT (September 2003) NATIONAL CANCER INSTITUTE, UNIVERSITY OF
NEBRASKA, KANSAS UNIVERSITY, AND UNIVERSITY OF IOWA JOINT PAPER.

Title: Integrative assessment of multiple pesticides as risk factors for
non-Hodgkin's lymphoma among men.

Authors: De Roos A J; Zahm S H; Cantor K P; Weisenburger D D; Holmes F F;
Burmeister L F; Blair

Authors affiliation: A Division of Cancer Epidemiology and Genetics,
National Cancer Institute, USA. University of Nebraska Medical Center,
Omaha, NE, USA. Kansas University Medical Center, Kansas City, KS, USA.
University of Iowa College of Medicine, Iowa City, IA,

Published in: USA OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2003 Sep),
volumn 60(9), E11. (it is not yet up on their website, their most recent
issue is the August issue).

Abstract: "BACKGROUND: An increased rate of non-Hodgkin's lymphoma (NHL) has
been repeatedly observed among farmers, but identification of specific
exposures that explain this observation has proven difficult. METHODS:
During the 1980s, the National Cancer Institute conducted three case-control
studies of NHL in the midwestern United States. These pooled data were used
to examine pesticide exposures in farming as risk factors for NHL in men.
The large sample size (n = 3417) allowed analysis of 47 pesticides
simultaneously, controlling for potential confounding by other pesticides in
the model, and adjusting the estimates based on a prespecified variance to
make them more stable. RESULTS: Reported use of several individual
pesticides was associated with increased NHL incidence, including
organophosphate insecticides coumaphos, diazinon, and fonofos, insecticides
chlordane, dieldrin, and copper acetoarsenite, and herbicides atrazine,
glyphosate, and sodium chlorate. A subanalysis of these "potentially
carcinogenic" pesticides suggested a positive trend of risk with exposure to
increasing numbers. CONCLUSION: Consideration of multiple exposures is
important in accurately estimating specific effects and in evaluating
realistic exposure scenarios."

Henry Kuska, retired

http://home.neo.rr.com/kuska/