am an MBA student BRBR
Natural products which a
1) Impossible, extremely difficult, or extremely expensive to synthesize in
bulk BRBR

Common sense.

2) Hard or inefficient to isolate from natural sources BRBR

Maple sap

3) Of commercial interest to pharmaceutical, vitamin, food, or cosmetic
industries BRBR

Both of the above.

4) The biosynthetic pathway (genes) has been outlined BRBR

Maple sap, yes. Dunno if there is a gene for common sense. Some of us have it;
some don't. It is not confined to humans.
Iris,
Central NY, Zone 5a, Sunset Zone 40
"If we see light at the end of the tunnel, It's the light of the oncoming
train."
Robert Lowell (1917-1977)