In article ,
Rick wrote:


Oh- I use Lysol too.

-Rick

Why ? We live in a world of microbes killing a few million won't
matter. Much better to coexist and enjoy real cheese then to think
sterility is the way to live. Consider asthma and the problem that
occur when the immune system is not challenged.

Bill who appreciates Billy's rants. Truth is not always pleasant.

............

1: Allergy. 2009 May;64(5):678-701.
Links

Scientific rationale for the Finnish Allergy Programme 2008-2018:
emphasis on prevention and endorsing tolerance.
von Hertzen LC, Savolainen J, Hannuksela M, Klaukka T, Lauerma A, Makela
MJ, Pekkanen J, Pietinalho A, Vaarala O, Valovirta E, Vartiainen E,
Haahtela T.
Skin and Allergy Hospital, Helsinki University Central Hospital,
Helsinki, Finland.

In similarity to many other western countries, the burden of allergic
diseases in Finland is high.

Studies worldwide have shown that an environment rich in microbes
in early life reduces the subsequent risk of developing allergic
diseases.


Along with urbanization, such exposure has dramatically reduced, both
in terms of diversity and quantity. Continuous stimulation of the immune
system by environmental saprophytes via the skin, respiratory tract and
gut appears to be necessary for activation of the regulatory network
including regulatory T-cells and dendritic cells. Substantial evidence
now shows that the balance between allergy and tolerance is dependent on
regulatory T-cells. Tolerance induced by allergen-specific regulatory
T-cells appears to be the normal immunological response to allergens in
non atopic healthy individuals. Healthy subjects have an intact
functional allergen-specific regulatory T-cell response, which in
allergic subjects is impaired. Evidence on this exists with respect to
atopic dermatitis, contact dermatitis, allergic rhinitis and asthma.
Restoration of impaired allergen-specific regulatory T-cell response and
tolerance induction has furthermore been demonstrated during
allergen-specific subcutaneous and sublingual immunotherapy and is
crucial for good therapeutic outcome. However, tolerance can also be
strengthened unspecifically by simple means, e.g. by consuming farm milk
and spending time in nature. Results so far obtained from animal models
indicate that it is possible to restore tolerance by administering the
allergen in certain circumstances both locally and systemically. It has
become increasingly clear that continuous exposure to microbial antigens
as well as allergens in foodstuffs and the environment is decisive, and
excessive antigen avoidance can be harmful and weaken or even prevent
the development of regulatory mechanisms. Success in the Finnish Asthma
Programme was an encouraging example of how it is possible to reduce
both the costs and morbidity of asthma. The time, in the wake of the
Asthma Programme, is now opportune for a national allergy programme,
particularly as in the past few years, fundamentally more essential data
on tolerance and its mechanisms have been published. In this review, the
scientific rationale for the Finnish Allergy Programme 2008-2018 is
outlined. The focus is on tolerance and how to endorse tolerance at the
population level.
PMID: 19383025 [PubMed - in process]

--
Garden in shade zone 5 S Jersey USA

Not all who wander are lost.
- J.R.R. Tolkien (1892-1973)