In message . com,
Biotech-lover writes
Hi Dears,
I have a Question..
No body knows why Colchicum Can continues its growth throught having
Colchicine?
!All of us know The colchicine is an anticancer & antimitosis
agent...so the question is that

Since no-one else has answered.

Colchicum is not the only plant genus producing tubliin-binding agents.
The anti-cancer drugs from Catharanthus, Podophyllum and Taxus all work
in that way.

I can think of three ways in which Colchicum can avoid the toxic effects
of colchicine.

1) It may have modified tubilins which lack the binding site.
2) It may sequestrate colchicine physically in locations away from the
meristem, so that it doesn't affect the growth of Colchicum, but is
released when the plant is eaten.
3) It may sequestrate colchicine chemically, so that it doesn't affect
the growth of Colchicum, but is released when the plant is eaten
(compare with cyanogenic glyocosides in Rosaceae).

I don't know which, if any, of these explanations applies. You might be
able to find an answer with Google, but it doesn't seem to fall out
readily.
--
Stewart Robert Hinsley