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#1
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!Need Help
Hi Dears,
I have a Question.. No body knows why Colchicum Can continues its growth throught having Colchicine? !All of us know The colchicine is an anticancer & antimitosis agent...so the question is that |
#2
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!Need Help
In message . com,
Biotech-lover writes Hi Dears, I have a Question.. No body knows why Colchicum Can continues its growth throught having Colchicine? !All of us know The colchicine is an anticancer & antimitosis agent...so the question is that Since no-one else has answered. Colchicum is not the only plant genus producing tubliin-binding agents. The anti-cancer drugs from Catharanthus, Podophyllum and Taxus all work in that way. I can think of three ways in which Colchicum can avoid the toxic effects of colchicine. 1) It may have modified tubilins which lack the binding site. 2) It may sequestrate colchicine physically in locations away from the meristem, so that it doesn't affect the growth of Colchicum, but is released when the plant is eaten. 3) It may sequestrate colchicine chemically, so that it doesn't affect the growth of Colchicum, but is released when the plant is eaten (compare with cyanogenic glyocosides in Rosaceae). I don't know which, if any, of these explanations applies. You might be able to find an answer with Google, but it doesn't seem to fall out readily. -- Stewart Robert Hinsley |
#3
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!Need Help
Hi stewart..
Thanks for your help! az you mentioned i couldn't fall out the answer readily..in Google so it was My last & maybe best opportunity to find my answer anyway If you can help me more I'll be glad my friend.. Good Luck |
#4
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!Need Help
In message . com,
Biotech-lover writes Hi stewart.. Thanks for your help! az you mentioned i couldn't fall out the answer readily..in Google so it was My last & maybe best opportunity to find my answer anyway If you can help me more I'll be glad my friend.. Good Luck I hope you haven't misunderstood me; what I've given you is speculation, not an answer. It was offered in the hope that it might help by providing a focus for subsequent investigation. -- Stewart Robert Hinsley |
#6
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!Need Help
hi
i've read about ur question and one Chinese book says that Colchicum is a kind of alkaloid, which is a kind of secondary metabolite that plants produce..the alkaloid is hold in the laticiferous tube (a kind of internal secretory structure) so this may be why it has no direct effect on plant cells but are used to protect themselves, attract insects(esp.entomoplily plants) or sth. like that.. its difficult for me to use english so i may not discribe it accurately...u'd better look for some more info.. |
#7
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!Need Help
Hi ,thank you so much
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