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#61
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wild to cultivated changes?
Wow, out of control software... Not sure how that last one ended up
getting sent three times. Guess it was a spectacularly good post!! Rob -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#62
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wild to cultivated changes?
Wow, out of control software... Not sure how that last one ended up
getting sent three times. Guess it was a spectacularly good post!! Rob -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#63
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wild to cultivated changes?
Ted Byers wrote:
Interesting. I wonder if they could have rejuvenated the cell Dolly was made from, before it began to divide, by turning back on. If so, would it turn itself off again at the right time, or would an intervention be required to turn it off later? Or is an exprimental manipulation to lengthen the telomeres without turning on the gene (perhaps be extracting the genetic material, manipulating it and then putting it back)? I'd wager that somebody is working on something similar. I don't really know what is going on in the cloning world. I do know it isn't quite as simple as just resetting telomere length. DNA damage and (perhaps) the accumulation of damage in long lived proteins play a role as well. Interestingly, this doesn't really apply to orchids, which are effectively immortal. Or if it does, the meristematic region of an orchid would be the equivalent of an eternally young tissue. It is interesting to consider what mechanism could allow a plant to continue to grow forever, but limits the age of animals. Nope! But then, those who fear death would likely want it examined in animals to see if the problems associated with turning telomerase on can be avoided, in an effort to prolong life. Through my own chronic illness (no safe, effective treatment and uncontrollable pain: less than a 50% chance of living to age 65 according to the latest stats I've seen), I have learned not only not to fear death but to see it as a welcome friend. What good is a prolonged life if you don't have your health? Indeed, and I wish you well with your illness. The worst day above the ground is better than the best below it... I'm reasonably confident there will be ways to prolong quality life in the very near future. There already have been substantial advances in lifespan and quality of life, just in the last 50 years or so. By quality I mean active and healthy. So if people could be as active at 80 as they are at 60, that would be a substantial improvement, even if total lifespan didn't increase. Prolonging life is no good, if that extra time is spent in hospital. This will end up really changing our social structure, of course, and I don't know if we are ready for it yet. We'll probably all need to work until 80 anyway, just to pay off the U.S. deficit. -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#64
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Wow, out of control software... Not sure how that last one ended up getting sent three times. Guess it was a spectacularly good post!! Evidence of ghosts in the machine! ;-) ;-) Cheers, Ted |
#65
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Wow, out of control software... Not sure how that last one ended up getting sent three times. Guess it was a spectacularly good post!! Evidence of ghosts in the machine! ;-) ;-) Cheers, Ted |
#66
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Indeed, and I wish you well with your illness. Thanks. The disease is diabetes, and the symptom that is particularly debilitating is the neuropathy that comes with it. This nueropathy generally results in altered sensation: temperature extremes are often not felt (and since they're not felt, it is easy to receive even third degree burns without knowing it), and physical damage is often not felt (which is why diabetics frequently lose limbs - they've stepped on broken glass or a mail or something, and the resulting would got sufficiently badly infected that gangrene sets in leading to the loss of the limb if detected early enough to prevent death), and finally, if often produces phantom pain in which it feels like you're enfuring the worst imaginable tortures and yet there is no corresponding injury. And then, of course, there ae all the other diseases, such as kidney disease, heart disease, &.c for which diabetics are quite vulnerable. There isn't an organ in the body that isn't at risk because of diabetes. Low blood sugar can lead to a coma, while high blood sugar levels does plenty of damage to all organs in the body. While insulin and medications like metformin, and a couple others, are useful in controlling blood sugar levels, there is nothing that can be done for the neuropathy that I believe to be both safe and effective. And diabetes will become an ever increasing problem since the incidence of it in north america is increasing (not too surprising since the single largest factor in its onset appears to be stress). The worst day above :-) This can be taken two more ways (both being logically valid, given implied assumptions). 1) The worst day in heaven is better than the best day on earth. 2) The worst day on earth is better than the best day in hell. Cheers, Ted |
#67
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Indeed, and I wish you well with your illness. Thanks. The disease is diabetes, and the symptom that is particularly debilitating is the neuropathy that comes with it. This nueropathy generally results in altered sensation: temperature extremes are often not felt (and since they're not felt, it is easy to receive even third degree burns without knowing it), and physical damage is often not felt (which is why diabetics frequently lose limbs - they've stepped on broken glass or a mail or something, and the resulting would got sufficiently badly infected that gangrene sets in leading to the loss of the limb if detected early enough to prevent death), and finally, if often produces phantom pain in which it feels like you're enfuring the worst imaginable tortures and yet there is no corresponding injury. And then, of course, there ae all the other diseases, such as kidney disease, heart disease, &.c for which diabetics are quite vulnerable. There isn't an organ in the body that isn't at risk because of diabetes. Low blood sugar can lead to a coma, while high blood sugar levels does plenty of damage to all organs in the body. While insulin and medications like metformin, and a couple others, are useful in controlling blood sugar levels, there is nothing that can be done for the neuropathy that I believe to be both safe and effective. And diabetes will become an ever increasing problem since the incidence of it in north america is increasing (not too surprising since the single largest factor in its onset appears to be stress). The worst day above :-) This can be taken two more ways (both being logically valid, given implied assumptions). 1) The worst day in heaven is better than the best day on earth. 2) The worst day on earth is better than the best day in hell. Cheers, Ted |
#68
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wild to cultivated changes?
Ted Byers wrote:
Interesting. I wonder if they could have rejuvenated the cell Dolly was made from, before it began to divide, by turning back on. If so, would it turn itself off again at the right time, or would an intervention be required to turn it off later? Or is an exprimental manipulation to lengthen the telomeres without turning on the gene (perhaps be extracting the genetic material, manipulating it and then putting it back)? I'd wager that somebody is working on something similar. I don't really know what is going on in the cloning world. I do know it isn't quite as simple as just resetting telomere length. DNA damage and (perhaps) the accumulation of damage in long lived proteins play a role as well. Interestingly, this doesn't really apply to orchids, which are effectively immortal. Or if it does, the meristematic region of an orchid would be the equivalent of an eternally young tissue. It is interesting to consider what mechanism could allow a plant to continue to grow forever, but limits the age of animals. Nope! But then, those who fear death would likely want it examined in animals to see if the problems associated with turning telomerase on can be avoided, in an effort to prolong life. Through my own chronic illness (no safe, effective treatment and uncontrollable pain: less than a 50% chance of living to age 65 according to the latest stats I've seen), I have learned not only not to fear death but to see it as a welcome friend. What good is a prolonged life if you don't have your health? Indeed, and I wish you well with your illness. The worst day above the ground is better than the best below it... I'm reasonably confident there will be ways to prolong quality life in the very near future. There already have been substantial advances in lifespan and quality of life, just in the last 50 years or so. By quality I mean active and healthy. So if people could be as active at 80 as they are at 60, that would be a substantial improvement, even if total lifespan didn't increase. Prolonging life is no good, if that extra time is spent in hospital. This will end up really changing our social structure, of course, and I don't know if we are ready for it yet. We'll probably all need to work until 80 anyway, just to pay off the U.S. deficit. -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#69
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wild to cultivated changes?
Ted Byers wrote:
Interesting. I wonder if they could have rejuvenated the cell Dolly was made from, before it began to divide, by turning back on. If so, would it turn itself off again at the right time, or would an intervention be required to turn it off later? Or is an exprimental manipulation to lengthen the telomeres without turning on the gene (perhaps be extracting the genetic material, manipulating it and then putting it back)? I'd wager that somebody is working on something similar. I don't really know what is going on in the cloning world. I do know it isn't quite as simple as just resetting telomere length. DNA damage and (perhaps) the accumulation of damage in long lived proteins play a role as well. Interestingly, this doesn't really apply to orchids, which are effectively immortal. Or if it does, the meristematic region of an orchid would be the equivalent of an eternally young tissue. It is interesting to consider what mechanism could allow a plant to continue to grow forever, but limits the age of animals. Nope! But then, those who fear death would likely want it examined in animals to see if the problems associated with turning telomerase on can be avoided, in an effort to prolong life. Through my own chronic illness (no safe, effective treatment and uncontrollable pain: less than a 50% chance of living to age 65 according to the latest stats I've seen), I have learned not only not to fear death but to see it as a welcome friend. What good is a prolonged life if you don't have your health? Indeed, and I wish you well with your illness. The worst day above the ground is better than the best below it... I'm reasonably confident there will be ways to prolong quality life in the very near future. There already have been substantial advances in lifespan and quality of life, just in the last 50 years or so. By quality I mean active and healthy. So if people could be as active at 80 as they are at 60, that would be a substantial improvement, even if total lifespan didn't increase. Prolonging life is no good, if that extra time is spent in hospital. This will end up really changing our social structure, of course, and I don't know if we are ready for it yet. We'll probably all need to work until 80 anyway, just to pay off the U.S. deficit. -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#70
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wild to cultivated changes?
Ted Byers wrote:
Interesting. I wonder if they could have rejuvenated the cell Dolly was made from, before it began to divide, by turning back on. If so, would it turn itself off again at the right time, or would an intervention be required to turn it off later? Or is an exprimental manipulation to lengthen the telomeres without turning on the gene (perhaps be extracting the genetic material, manipulating it and then putting it back)? I'd wager that somebody is working on something similar. I don't really know what is going on in the cloning world. I do know it isn't quite as simple as just resetting telomere length. DNA damage and (perhaps) the accumulation of damage in long lived proteins play a role as well. Interestingly, this doesn't really apply to orchids, which are effectively immortal. Or if it does, the meristematic region of an orchid would be the equivalent of an eternally young tissue. It is interesting to consider what mechanism could allow a plant to continue to grow forever, but limits the age of animals. Nope! But then, those who fear death would likely want it examined in animals to see if the problems associated with turning telomerase on can be avoided, in an effort to prolong life. Through my own chronic illness (no safe, effective treatment and uncontrollable pain: less than a 50% chance of living to age 65 according to the latest stats I've seen), I have learned not only not to fear death but to see it as a welcome friend. What good is a prolonged life if you don't have your health? Indeed, and I wish you well with your illness. The worst day above the ground is better than the best below it... I'm reasonably confident there will be ways to prolong quality life in the very near future. There already have been substantial advances in lifespan and quality of life, just in the last 50 years or so. By quality I mean active and healthy. So if people could be as active at 80 as they are at 60, that would be a substantial improvement, even if total lifespan didn't increase. Prolonging life is no good, if that extra time is spent in hospital. This will end up really changing our social structure, of course, and I don't know if we are ready for it yet. We'll probably all need to work until 80 anyway, just to pay off the U.S. deficit. -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#71
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wild to cultivated changes?
Wow, out of control software... Not sure how that last one ended up
getting sent three times. Guess it was a spectacularly good post!! Rob -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#72
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wild to cultivated changes?
Wow, out of control software... Not sure how that last one ended up
getting sent three times. Guess it was a spectacularly good post!! Rob -- Rob's Rules: http://www.msu.edu/~halgren 1) There is always room for one more orchid 2) There is always room for two more orchids 2a. See rule 1 3) When one has insufficient credit to purchase more orchids, obtain more credit |
#73
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Wow, out of control software... Not sure how that last one ended up getting sent three times. Guess it was a spectacularly good post!! Evidence of ghosts in the machine! ;-) ;-) Cheers, Ted |
#74
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Wow, out of control software... Not sure how that last one ended up getting sent three times. Guess it was a spectacularly good post!! Evidence of ghosts in the machine! ;-) ;-) Cheers, Ted |
#75
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wild to cultivated changes?
"Rob Halgren" wrote in message ... Indeed, and I wish you well with your illness. Thanks. The disease is diabetes, and the symptom that is particularly debilitating is the neuropathy that comes with it. This nueropathy generally results in altered sensation: temperature extremes are often not felt (and since they're not felt, it is easy to receive even third degree burns without knowing it), and physical damage is often not felt (which is why diabetics frequently lose limbs - they've stepped on broken glass or a mail or something, and the resulting would got sufficiently badly infected that gangrene sets in leading to the loss of the limb if detected early enough to prevent death), and finally, if often produces phantom pain in which it feels like you're enfuring the worst imaginable tortures and yet there is no corresponding injury. And then, of course, there ae all the other diseases, such as kidney disease, heart disease, &.c for which diabetics are quite vulnerable. There isn't an organ in the body that isn't at risk because of diabetes. Low blood sugar can lead to a coma, while high blood sugar levels does plenty of damage to all organs in the body. While insulin and medications like metformin, and a couple others, are useful in controlling blood sugar levels, there is nothing that can be done for the neuropathy that I believe to be both safe and effective. And diabetes will become an ever increasing problem since the incidence of it in north america is increasing (not too surprising since the single largest factor in its onset appears to be stress). The worst day above :-) This can be taken two more ways (both being logically valid, given implied assumptions). 1) The worst day in heaven is better than the best day on earth. 2) The worst day on earth is better than the best day in hell. Cheers, Ted |
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