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#1
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DNA sequence question
K Barrett wrote:
Scientists sequenced the genome of the honeybee. http://www.sciencenews.org/articles/20061028/fob1.asp In this article the reporter writes "Among the novelties of the honeybee, Apis mellifera, are its 170 genes for odor receptors." (snip) But if this is the first time a species' genome has been looked at and if there are only 5 other insects that have had their genome cracked, much less studied, then 'How do they know?" By comparison with known odor receptor genes in fruit flies, Drosophila melanogaster. It doesn't actually matter how many insects have had their genomes sequenced. What matters is that fruitflies have been sequenced, AND their genes have been mutated to see what they do. |
#3
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DNA sequence question
Thank you both for answering.
K "Rob" wrote in message ... wrote: K Barrett wrote: Scientists sequenced the genome of the honeybee. http://www.sciencenews.org/articles/20061028/fob1.asp In this article the reporter writes "Among the novelties of the honeybee, Apis mellifera, are its 170 genes for odor receptors." (snip) But if this is the first time a species' genome has been looked at and if there are only 5 other insects that have had their genome cracked, much less studied, then 'How do they know?" By comparison with known odor receptor genes in fruit flies, Drosophila melanogaster. It doesn't actually matter how many insects have had their genomes sequenced. What matters is that fruitflies have been sequenced, AND their genes have been mutated to see what they do. Yep. We bioinformatics geeks do this all the time. It doesn't much matter that we haven't figured out all the honeybee genes, it does matter that we know a lot about related genes in other organisms. The 170 genes were probably mostly predicted computationally. We know what coding DNA looks like from experience with other organisms. We assume that it is similar in 'unknown' organisms. It is a computational model (probably several different ones) that of course isn't perfect. Perhaps some of those 170 genes aren't real, or slightly mis-predicted. But we might have missed a few, too. -- Rob's Rules: http://littlefrogfarm.com 1) There is always room for one more orchid 2) There is always room for two more orchids 2a) See rule 1 3) When one has insufficient credit to obtain more orchids, obtain more credit |
#4
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DNA sequence question
Well it's simple Kathy, I was kicked out of science class for turning on
the Bunson Burners ( in a 3rd world class in Africa) Anyway it's all in the genes. If you don't gnome the mutant then leave it to the odor receptors! HaH! Cheers Wendy email Address Invalid K Barrett wrote: Thank you both for answering. K "Rob" wrote in message ... wrote: K Barrett wrote: Scientists sequenced the genome of the honeybee. http://www.sciencenews.org/articles/20061028/fob1.asp In this article the reporter writes "Among the novelties of the honeybee, Apis mellifera, are its 170 genes for odor receptors." (snip) But if this is the first time a species' genome has been looked at and if there are only 5 other insects that have had their genome cracked, much less studied, then 'How do they know?" By comparison with known odor receptor genes in fruit flies, Drosophila melanogaster. It doesn't actually matter how many insects have had their genomes sequenced. What matters is that fruitflies have been sequenced, AND their genes have been mutated to see what they do. Yep. We bioinformatics geeks do this all the time. It doesn't much matter that we haven't figured out all the honeybee genes, it does matter that we know a lot about related genes in other organisms. The 170 genes were probably mostly predicted computationally. We know what coding DNA looks like from experience with other organisms. We assume that it is similar in 'unknown' organisms. It is a computational model (probably several different ones) that of course isn't perfect. Perhaps some of those 170 genes aren't real, or slightly mis-predicted. But we might have missed a few, too. -- Rob's Rules: http://littlefrogfarm.com 1) There is always room for one more orchid 2) There is always room for two more orchids 2a) See rule 1 3) When one has insufficient credit to obtain more orchids, obtain more credit |
#5
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DNA sequence question
Nothing makes you feel older than finding out everyting you were taught
isn't true anymore. K "wendy7" wrote in message ... Well it's simple Kathy, I was kicked out of science class for turning on the Bunson Burners ( in a 3rd world class in Africa) Anyway it's all in the genes. If you don't gnome the mutant then leave it to the odor receptors! HaH! Cheers Wendy email Address Invalid K Barrett wrote: Thank you both for answering. K "Rob" wrote in message ... wrote: K Barrett wrote: Scientists sequenced the genome of the honeybee. http://www.sciencenews.org/articles/20061028/fob1.asp In this article the reporter writes "Among the novelties of the honeybee, Apis mellifera, are its 170 genes for odor receptors." (snip) But if this is the first time a species' genome has been looked at and if there are only 5 other insects that have had their genome cracked, much less studied, then 'How do they know?" By comparison with known odor receptor genes in fruit flies, Drosophila melanogaster. It doesn't actually matter how many insects have had their genomes sequenced. What matters is that fruitflies have been sequenced, AND their genes have been mutated to see what they do. Yep. We bioinformatics geeks do this all the time. It doesn't much matter that we haven't figured out all the honeybee genes, it does matter that we know a lot about related genes in other organisms. The 170 genes were probably mostly predicted computationally. We know what coding DNA looks like from experience with other organisms. We assume that it is similar in 'unknown' organisms. It is a computational model (probably several different ones) that of course isn't perfect. Perhaps some of those 170 genes aren't real, or slightly mis-predicted. But we might have missed a few, too. -- Rob's Rules: http://littlefrogfarm.com 1) There is always room for one more orchid 2) There is always room for two more orchids 2a) See rule 1 3) When one has insufficient credit to obtain more orchids, obtain more credit |
#6
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DNA sequence question
K Barrett wrote:
Nothing makes you feel older than finding out everyting you were taught isn't true anymore. It's even worse when it's your job. Research that required three years of late nights in the lab when I was a grad student now takes about 15 minutes on the computer. Many of the techniques that I learned are completely obsolete, and it has been less than ten years since I defended my dissertation. Nick |
#7
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DNA sequence question
I saw a TV show on my new 60" HD TV about a census of marine micro organisms
that is currently underway. They are using cutting edge genetic sequencing tools to count new micro organisms in sea water. They collect the water, strain it through ever finer filters to collect a gooey glob of micro organisms and then they extract their DNA by slicing it into tiny nucleotide bits, then they replicate these bits, then they REASSEMBLE them back into complete genomes....and out of this gene puree and reassembly process comes something a computer program can use to count the number of unique organisms that were in the sea water sample BEFORE they were chopped to bits. One of the remarkable things they have discovered, other than the Amazing and unpredictably large number of new species at the microscopic level are lots of gene groups with interesting mutations on gene groups which they already know are used by these organisms to do things like turn light into energy, break down oily carbon compounds, enhance immunity to cold, etc. It is just scary what bags of genes called 'humans' can infer about themselves based on what is literally a sampling of their gene pool. wrote in message oups.com... K Barrett wrote: Nothing makes you feel older than finding out everyting you were taught isn't true anymore. It's even worse when it's your job. Research that required three years of late nights in the lab when I was a grad student now takes about 15 minutes on the computer. Many of the techniques that I learned are completely obsolete, and it has been less than ten years since I defended my dissertation. Nick |
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